Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of polymorphisms in TRAILR1 and TNFR1A on the response to anti-TNF therapies in patients with rheumatoid and psoriatic arthritis.

Joint bone spine - 1 Dec 2012

Morales-Lara María José, Cañete Juan D, Torres-Moreno Daniel, Hernández María Victoria, Pedrero Francisco, Celis Raquel, García-Simón María Sergia, Conesa-Zamora Pablo

Abstract excerpt

OBJECTIVES: As the role of polymorphisms in death receptors (DRs) such as Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor 1 (TRAIL-R1) and Tumor Necrosis Factor Receptor 1A (TNF-R1A) on the response to anti-TNF therapy remains unknown, we evaluated the association between TRAILR1 and TNFR1A gene polymorphisms (rs20575/C626G and rs767455/G36A) and the pharmacogenetics of patients with rheumatoid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adalimumab
Share to Antirheumatic Agents
Share to Arthritis, Psoriatic
Share to Etanercept
Share to Infliximab
Share to Receptors, TNF-Related Apoptosis-Inducing Ligand
Share to Receptors, Tumor Necrosis Factor
Share to Receptors, Tumor Necrosis Factor, Type I

Source

Identifiers

PMID: 22480748
DOI: 10.1016/j.jbspin.2012.02.003

Genes

TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of polymorphisms in TRAILR1 and TNFR1A on the response to anti-TNF therapies in patients with rheumatoid and psoriatic arthritis.PMID 22480748Read ↗

Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study.Semantic proximity Read ↗

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.Semantic proximity Read ↗

Analysis of associations between polymorphisms within genes coding for tumour necrosis factor (TNF)-alpha and TNF receptors and responsiveness to TNF-alpha blockers in patients with rheumatoid arthritis.Semantic proximity Read ↗

Pharmacogenetic analysis of TNF, TNFRSF1A, and TNFRSF1B gene polymorphisms and prediction of response to anti-TNF therapy in psoriasis patients in the Greek population.Semantic proximity Read ↗

Can tumor necrosis factor receptor II gene 676T>G polymorphism predict the response grading to anti-TNFalpha therapy in rheumatoid arthritis?Semantic proximity Read ↗

Combined tumour necrosis factor- and tumour necrosis factor receptor genotypes could predict rheumatoid arthritis patients' response to anti-TNF- therapy and explain controversies of studies based on a single polymorphismSemantic proximity Read ↗

Association between tumor necrosis factor-α (TNF-α) promoter -308 G/A and response to TNF-α blockers in rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Exploring pharmacogenetic variants for predicting response to anti-TNF therapy in autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis.Semantic proximity Read ↗

Genetics in TNF-TNFR pathway: A complex network causing spondyloarthritis and conditioning response to anti-TNFα therapy.Semantic proximity Read ↗

Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis.Semantic proximity Read ↗

Pharmacogenetics of etanercept: role of TNF-α gene polymorphisms in improving its efficacy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.