Article
Pharmacogenetics of etanercept: role of TNF-α gene polymorphisms in improving its efficacy.
Expert opinion on drug metabolism & toxicology - 1 Dec 2014
Murdaca Giuseppe, Spanò Francesca, Contatore Miriam, Guastalla Andrea, Magnani Ottavia, Puppo Francesco
Abstract excerpt
INTRODUCTION: During the last decade, many new biological immune modulators have entered the market as new therapeutic principles. Biologics, including TNF-α inhibitors, are the new frontier in the treatment of immune-mediated or inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease, ankylosing spondylitis, systemic sclerosis, disseminated granuloma annulare, psoriasis...
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