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Article

Genetic risk profiling and gene signature modeling to predict risk of complications after IPAA.

Diseases of the colon and rectum - 1 Mar 2012

Sehgal Rishabh, Berg Arthur, Polinski Joseph I, Hegarty John P, Lin Zhenwu, McKenna Kevin J, Stewart David B, Poritz Lisa S, Koltun Walter A

Abstract excerpt

BACKGROUND: Severe pouchitis and Crohn's disease-like complications are 2 adverse postoperative complications that confound the success of the IPAA in patients with ulcerative colitis. To date, approximately 83 single nucleotide polymorphisms within 55 genes have been associated with IBD. OBJECTIVE: The aim of this study was to identify single-nucleotide polymorphisms that correlate with complications after IPAA...

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Topics

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Share to Colitis
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to TNFSF15 gene

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Share to Nod2 Signaling Adaptor Protein

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 22469789
DOI: 10.1097/DCR.0b013e31823e2d18

Genes

NOD2
PTGER4
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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