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Article

Mutation in TAGAP is protective of anal sepsis in ileocolic Crohn's disease.

Diseases of the colon and rectum - 1 Nov 2012

Connelly Tara M, Sehgal Rishabh, Berg Arthur S, Hegarty John P, Deiling Sue, Stewart David B, Poritz Lisa S, Koltun Walter A

Abstract excerpt

BACKGROUND: Anal complications of Crohn's disease range from painless skin tags to debilitating fistulas that are imperfectly treated with tumor necrosis factor antagonists. The recent discovery of more than 190 single-nucleotide polymorphisms associated with Crohn's disease offers the opportunity to genetically define the severity of anal disease in Crohn's disease and possibly predict prognosis and anti-tumor...

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Source

Identifiers

PMID: 23044675
DOI: 10.1097/DCR.0b013e3182676931

Genes

TAGAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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