Article
Genetic risk profiling and prediction of disease course in Crohn's disease patients.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2009
Henckaerts Liesbet, Van Steen Kristel, Verstreken Isabel, Cleynen Isabelle, Franke Andre, Schreiber Stefan, Rutgeerts Paul, Vermeire Séverine
Abstract excerpt
BACKGROUND & AIMS: Clinical presentation at diagnosis and disease course of Crohn's disease (CD) are heterogeneous and variable over time. Early introduction of immunomodulators and/or biologicals might be justified in patients at risk for disease progression, so it is important to identify these patients as soon as possible. We examined the influence of recently discovered CD-associated susceptibility loci on...
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