Article
Crohn's disease-associated genetic marker is seen in medically unresponsive ulcerative colitis patients and may be associated with pouch-specific complications.
Diseases of the colon and rectum - 1 May 1999
Facklis K, Plevy S E, Vasiliauskas E A, Kam L, Taylor K, Targan S R, Fleshner P R
Abstract excerpt
PURPOSE: Genetic markers have been used to define subgroups of patients within the broad categories of Crohn's disease and ulcerative colitis that may differ in clinical course and response to medical therapy. The tumor necrosis factor microsatellite haplotype a2blc2d4e1 has been found previously to be present in 24 percent of patients with Crohn's disease and only 5 percent of patients with ulcerative colitis....
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