Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 a susceptibility factor?

Inflammatory bowel diseases - 1 Nov 2005

Meier Carmen B, Hegazi Refaat A, Aisenberg James, Legnani Peter E, Nilubol Naris, Cobrin Gena M, Duerr Richard H, Gorfine Stephen R, Bauer Joel J, Sachar David B, Plevy Scott E

Abstract excerpt

BACKGROUND: Pouchitis is a frequent complication after ileal pouch-anal anastamosis (IPAA) for ulcerative colitis (UC). The aim of this study was to determine whether genetic polymorphisms in the innate immune receptors toll-like receptor (TLR)4 and caspase activation and recruitment domain family member 15 (CARD15) genes are associated with pouchitis. METHODS: From a retrospectively ascertained cohort of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Colitis, Ulcerative

Share to Genetic Predisposition to Disease

Share to Intracellular Signaling Peptides and Proteins

Share to Nod2 Signaling Adaptor Protein

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16239841
DOI: 10.1097/01.mib.0000186407.25694.cf

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 a susceptibility factor?PMID 16239841Read ↗

NOD2/CARD15 mutations correlate with severe pouchitis after ileal pouch-anal anastomosis.Semantic proximity Read ↗

CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response.Semantic proximity Read ↗

Combined carriership of TLR9-1237C and CD14-260T alleles enhances the risk of developing chronic relapsing pouchitis.Semantic proximity Read ↗

Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults.Semantic proximity Read ↗

Epithelioid granulomas, pattern recognition receptors, and phenotypes of Crohn's disease.Semantic proximity Read ↗

Role of the CARD15 gene in the pathogenesis of Crohn disease: phenotypic classification and prognostic implications.Semantic proximity Read ↗

CARD 15 and toll-like receptors: the link with Crohn's disease.Semantic proximity Read ↗

Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease.Semantic proximity Read ↗

CARD15 gene polymorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis.Semantic proximity Read ↗

CARD15 genotyping in inflammatory bowel disease patients by multiplex pyrosequencing.Semantic proximity Read ↗

Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.Semantic proximity Read ↗

CARD15 gene variants and risk of reoperation in Crohn's disease patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.