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Article

Crohn's disease-related single nucleotide polymorphisms are associated with ileal pouch afferent limb stenosis.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Sept 2021

O'Brien Stephen J, Hallion Jacob, Scheurlen Katharina M, Fiechter Casey, Burton James, Paas Mason, Schmidt Miranda, Gardner Sarah, Eichenberger Maurice R, Pan Jianmin, Rai Shesh, Galandiuk Susan

Abstract excerpt

BACKGROUND: Ileal pouch-anal anastomosis (IPAA) is a common surgical treatment for ulcerative colitis. Afferent limb stenosis is an infrequent complication following IPAA, suggesting underlying Crohn's disease (CD). We hypothesized that CD-related single nucleotide polymorphisms (SNPs) are associated with afferent limb stenosis. METHODS: Afferent limb stenosis and CD control group patients were recruited from a...

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Share to Colitis, Ulcerative
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33443688
DOI: 10.1007/s11605-020-04884-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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