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Article

Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2012

Kuchay S M, Wieschhaus A J, Marinkovic M, Herman I M, Chishti A H

Abstract excerpt

BACKGROUND: Calpains are implicated in a wide range of cellular functions including the maintenance of hemostasis via the regulation of cytoskeletal modifications in platelets. OBJECTIVES: Determine the functional role of calpain isoforms in platelet spreading. METHODS AND RESULTS: Platelets from...

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Identifiers

PMID: 22458296
DOI: 10.1111/j.1538-7836.2012.04715.x
PMCID: PMC3956748

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22458296-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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