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Article

Reciprocal Signaling by Integrin and Nonintegrin Receptors during Collagen Activation of Platelets

29 Jun 2003

Abstract excerpt

Activation of platelets by exposed collagen after vessel wall injury is a primary event in the pathogenesis of stroke and myocardial infarction. Two collagen receptors, integrin alpha2beta1 and glycoprotein VI (GPVI), are expressed at similar levels on human and mouse platelets, but their individual roles during collagen activation remain poorly defined. Recent genetic and pharmacologic experiments have revealed...

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Identifiers

PMID: 12832464
DOI: 10.1128/mcb.23.14.4764-4777.2003

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Reciprocal Signaling by Integrin and Nonintegrin Receptors during Collagen Activation of PlateletsPMID 12832464Read ↗

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Paired immunoglobulin-like receptor B regulates platelet activation.Semantic proximity Read ↗

The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formationSemantic proximity Read ↗

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