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Article

Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2017

Smith Christopher W, Thomas Steven G, Raslan Zaher, Patel Pushpa, Byrne Maxwell, Lordkipanidzé Marie, Bem Danai, Meyaard Linde, Senis Yotis A, Watson Steve P, Mazharian Alexandra

Abstract excerpt

OBJECTIVE: Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a collagen receptor that belongs to the inhibitory immunoreceptor tyrosine-based inhibition motif-containing receptor family. It is an inhibitor of signaling via the immunoreceptor tyrosine-based activation motif-containing collagen receptor complex, glycoprotein VI-FcRγ-chain. It is expressed on hematopoietic cells, including immature...

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Identifiers

PMID: 28336561
DOI: 10.1161/ATVBAHA.117.309253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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