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Article

Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series.

PloS one - 1 Jan 2012

Luedeke Manuel, Coinac Irina, Linnert Carmen M, Bogdanova Natalia, Rinckleb Antje E, Schrader Mark, Vogel Walther, Hoegel Josef, Meyer Andreas, Dörk Thilo, Maier Christiane

Abstract excerpt

Prostate cancer susceptibility has previously been associated with truncating germline variants in the gene TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1). For two apparently recurrent mutations (p.Q22fs and p.S32X) a remarkable OR of 5.1 was reported for prostate cancer risk. Since these findings have not been validated so far, we genotyped p.Q22fs and p.S32X in two German series with a...

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Identifiers

PMID: 22457820
DOI: 10.1371/journal.pone.0034128
PMCID: PMC3311578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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