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Article

Germline mutations in the p73 gene do not predispose to familial prostate-brain cancer.

The Prostate - 15 Sept 2001

Peters M A, Janer M, Kolb S, Jarvik G P, Ostrander E A, Stanford J L

Abstract excerpt

BACKGROUND: Analysis of high-risk prostate cancer (PC) families with at least one confirmed case of primary brain cancer (BC) has identified a region of genetic linkage on chromosome 1p36 termed CAPB. The p36 region of chromosome one has been reported to have frequent loss of heterozygosity (LOH) in brain and central nervous system (CNS) tumors and epidemiological studies have shown an increased relative risk of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11536309
DOI: 10.1002/pros.1109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline mutations in the p73 gene do not predispose to familial prostate-brain cancer.PMID 11536309Read ↗

Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36.Semantic proximity Read ↗

p73 mutations are not detected in sporadic and hereditary breast cancer.Semantic proximity Read ↗

Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility.Semantic proximity Read ↗

Mutation and expression analysis of the p73 gene in prostate cancer.Semantic proximity Read ↗

A candidate gene approach within the susceptibility region PCaP on 1q42.2-43 excludes deleterious mutations of the PCTA-1 gene to be responsible for hereditary prostate cancer.Semantic proximity Read ↗

Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.Semantic proximity Read ↗

Evaluation of DLC1 as a prostate cancer susceptibility gene: mutation screen and association study.Semantic proximity Read ↗

The p73 gene is not mutated in oligodendrogliomas which frequently have a deleted region at chromosome 1p36.3.Semantic proximity Read ↗

Sequence variants in the human 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1) gene are not associated with prostate cancer risk.Semantic proximity Read ↗

Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series.Semantic proximity Read ↗

Infrequent somatic mutations of the p73 gene in various human cancers.Semantic proximity Read ↗

Mutational analysis of the p73 gene in human breast cancers.Semantic proximity Read ↗

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