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Article

Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk.

Cancer research - 1 Nov 2006

Wang Xianshu, Wang Fengwei, Taniguchi Ken, Seelan Ratnam S, Wang Liang, Zarfas Katherine E, McDonnell Shannon K, Qian Chiping, Pan Kaifeng, Lu Youyong, Shridhar Viji, Couch Fergus J, Tindall Donald J, Beebe-Dimmer Jennifer L, Cooney Kathleen A, Isaacs William B, Jacobsen Steven J, Schaid Daniel J, Thibodeau Stephen N, Liu Wanguo

Abstract excerpt

Germ line mutations in several genes (BRCA1, BRCA2, and CHEK2) whose products are involved in the DNA damage-signaling pathway have been implicated in prostate cancer risk. To identify additional genes in this pathway that might confer susceptibility to this cancer, we analyzed a recently identif...

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Identifiers

PMID: 17079449
DOI: 10.1158/0008-5472.CAN-06-0638

Genes

BRCA1
BRCA2
CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17079449-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk.PMID 17079449Read ↗

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