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Article

Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat.

The American journal of pathology - 1 May 2012

Reynolds John, Cook Paul R, Behmoaras Jacques, Smith Jennifer, Bhangal Gurjeet, Tadros Susan, Tee Jonathan, Salama Alan D, Evans David J, Aitman Timothy J, Cook H Terence, Pusey Charles D

Abstract excerpt

In experimental autoimmune glomerulonephritis (EAG), a model of Goodpasture's disease, Wistar Kyoto (WKY) rats immunized with collagenase-solubilized glomerular basement membrane (GBM) or the recombinant NC1 domain of the α3 chain of type IV collagen [α3(IV)NC1] develop anti-GBM antibodies and focal necrotizing glomerulonephritis with crescent formation. However, Lewis (LEW) rats, which share the same major...

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Identifiers

PMID: 22445570
DOI: 10.1016/j.ajpath.2012.01.029
PMCID: PMC3532591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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