Article
Genetic predisposition for glomerulonephritis-induced glomerulosclerosis in rats is linked to chromosome 1.
Physiological genomics - 8 Oct 2008
Ijpelaar Daphne H T, Schulz Angela, Aben Joris, van der Wal Annemieke, Bruijn Jan A, Kreutz Reinhold, de Heer Emile
Abstract excerpt
Genetic factors influence renal disease progression, and several loci have been linked to the spontaneous development of proteinuria and glomerulosclerosis in animal models. However, the role of genetic susceptibility in glomerulonephritis-induced progressive glomerulosclerosis is unknown. In a rat model of mesangial proliferative glomerulonephritis, anti-Thy-1 glomerulonephritis (antiThy1GN), Lewis/Maastricht...
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