Article
Strain susceptibility to active induction and passive transfer of experimental autoimmune glomerulonephritis in the rat.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 2006
Reynolds John, Albouainain Amina, Duda Mark Anthony, Evans David John, Pusey Charles Dickson
Abstract excerpt
BACKGROUND: Previous studies have shown that different inbred rat strains vary in their susceptibility to experimental autoimmune glomerulonephritis (EAG). The Wistar Kyoto (WKY) rat is highly susceptible and develops crescentic glomerulonephritis, while the Lewis (LEW) rat is resistant. When immunized with collagenase-solubilized rat glomerular basement membrane (GBM), both strains produce circulating...
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