Article
Cancer and the bromodomains of BAF180.
Biochemical Society transactions - 1 Apr 2012
Brownlee Peter M, Chambers Anna L, Oliver Antony W, Downs Jessica A
Abstract excerpt
Chromatin remodelling complexes alter the structure of chromatin and have central roles in all DNA-templated activities, including regulation of gene expression and DNA repair. Mutations in subunits of the PBAF (polybromo/Brg1-associated factor) or SWI/SNF-B remodelling complex, including BAF180,...
Topics
- Animals
- Humans
- Mutation
- Neoplasms
- Nuclear Proteins
- Protein Binding
- Protein Structure, Tertiary
- Protein Subunits