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Article

BAF180: Its Roles in DNA Repair and Consequences in Cancer.

ACS chemical biology - 20 Oct 2017

Hopson Sarah, Thompson Martin J

Abstract excerpt

In 2011, Varela et al. reported that the PBRM1 gene is mutated in approximately 40% of clear cell renal cell carcinoma cases. Since then, the number of studies relating PBRM1 mutations to cancers has substantially increased. BAF180 has now been linked to more than 30 types of cancers, including ccRCC, cholangiocarcinomas, esophageal squamous cell carcinoma, bladder cancer, and breast cancer. The mutations...

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Source

Identifiers

PMID: 28921948
DOI: 10.1021/acschembio.7b00541

Genes

PBRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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