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Article

Profiles of epigenetic histone post-translational modifications at type 1 diabetes susceptible genes.

The Journal of biological chemistry - 11 May 2012

Miao Feng, Chen Zhuo, Zhang Lingxiao, Liu Zheng, Wu Xiwei, Yuan Yate-Ching, Natarajan Rama

Abstract excerpt

Both genetic and environmental factors are implicated in type 1 diabetes (T1D). Because environmental factors can trigger epigenetic changes, we hypothesized that variations in histone post-translational modifications (PTMs) at the promoter/enhancer regions of T1D susceptible genes may be associated with T1D. We therefore evaluated histone PTM variations at known T1D susceptible genes in blood cells from T1D...

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Share to Diabetes Mellitus, Type 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22431725
DOI: 10.1074/jbc.M111.330373
PMCID: PMC3351309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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