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Article

DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology.

Journal of autoimmunity - 1 May 2014

Stefan Mihaela, Zhang Weijia, Concepcion Erlinda, Yi Zhengzi, Tomer Yaron

Abstract excerpt

Type 1 diabetes (T1D) shows ∼40% concordance rate in monozygotic twins (MZ) suggesting a role for environmental factors and/or epigenetic modifications in the etiology of the disease. The aim of our study was to dissect the contribution of epigenetic factors, particularly, DNA methylation (DNAm),...

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Share to Antigens, Differentiation, T-Lymphocyte
Share to CpG Islands
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to HLA Antigens

Share to Oligonucleotide Array Sequence Analysis

Share to Twins, Monozygotic

Source

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Identifiers

PMID: 24210274
DOI: 10.1016/j.jaut.2013.10.001
PMCID: PMC3995844

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24210274-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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