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Article

Implication of epigenetic factors in the pathogenesis of type 1 diabetes.

Chinese medical journal - 1 Apr 2021

Zhang Jing, Chen Long-Min, Zou Yuan, Zhang Shu, Xiong Fei, Wang Cong-Yi

Abstract excerpt

ABSTRACT: Type 1 diabetes (T1D) is an autoimmune disease that resulted from the severe destruction of the insulin-producing β cells in the pancreases of individuals with a genetic predisposition. Genome-wide studies have identified HLA and other risk genes associated with T1D susceptibility in humans. However, evidence obtained from the incomplete concordance of diabetes incidence among monozygotic twins suggests...

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Share to Diabetes and associated disorders
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Genetic Predisposition to Disease

Share to Immune Cell Function and Interaction

Share to Incidence

Share to Pancreatic function and diabetes

Share to Twins, Monozygotic

Source

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Identifiers

PMID: 33813508
DOI: 10.1097/CM9.0000000000001450
PMCID: PMC8116022

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