Article
The Role of Epigenetics in Type 1 Diabetes.
Advances in experimental medicine and biology - 1 Jan 2020
Xie Zhiguo, Chang Christopher, Huang Gan, Zhou Zhiguang
Abstract excerpt
Type 1 diabetes (T1D) is an autoimmune disease caused by the interaction between genetic alterations and environmental factors. More than 60 susceptible genes or loci of T1D have been identified. Among them, HLA regions are reported to contribute about 50% of genetic susceptibility in Caucasians. There are many environmental factors involved in the pathogenesis of T1D. Environmental factors may change the...
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