Article
Genetic and epigenetic factors in etiology of diabetes mellitus type 1.
Pediatrics - 1 Dec 2013
Stankov Karmen, Benc Damir, Draskovic Dragan
Abstract excerpt
Diabetes mellitus type 1 (T1D) is a complex disease resulting from the interplay of genetic, epigenetic, and environmental factors. Recent progress in understanding the genetic basis of T1D has resulted in an increased recognition of childhood diabetes heterogeneity. After the initial success of family-based linkage analyses, which uncovered the strong linkage and association between HLA gene variants and T1D,...
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