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Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

23 Jan 2014

Abstract excerpt

We assessed whether epigenetic histone posttranslational modifications are associated with the prolonged beneficial effects (metabolic memory) of intensive versus conventional therapy during the Diabetes Control and Complications Trial (DCCT) on the progression of microvascular outcomes in the long-term Epidemiology of Diabetes Interventions and Complications (EDIC) study. We performed chromatin...

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PMID: 24458354
DOI: 10.2337/db13-1251

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