Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence features of retrotransposons allow for epigenetic variability.

eLife - 20 Oct 2021

Costello Kevin R, Leung Amy, Trac Candi, Lee Michael, Basam Mudaser, Pospisilik J Andrew, Schones Dustin E

Abstract excerpt

Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes to have function, the majority of these elements are epigenetically silenced by DNA methylation in somatic cells. However, some TEs in mice, including the Intracisternal A-particle (IAP) subfamily of retrotransposons, have been shown to display...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Epigenesis, Genetic
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Retroelements

Source

Open in PubMed Open full text

Identifiers

PMID: 34668484
DOI: 10.7554/eLife.71104
PMCID: PMC8555987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence features of retrotransposons allow for epigenetic variability.PMID 34668484Read ↗

Sequence features of retrotransposons allow for epigenetic variabilitySemantic proximity Read ↗

Retrotransposons as a major source of epigenetic variations in the mammalian genome.Semantic proximity Read ↗

Variably methylated retrotransposons are refractory to a range of environmental perturbations.Semantic proximity Read ↗

Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.Semantic proximity Read ↗

Epigenetic regulation of unique genes and repetitive elements by the KRAB zinc finger protein ZFP57Semantic proximity Read ↗

How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.Semantic proximity Read ↗

The KZFP/KAP1 system controls transposable elements-embedded regulatory sequences in adult T cellsSemantic proximity Read ↗

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage.Semantic proximity Read ↗

Variable methylation of endogenous retroviruses : epigenetic inheritance, environmental modulation, and genetic modifiersSemantic proximity Read ↗

Mouse metastable epialleles are extremely rare.Semantic proximity Read ↗

Non-essential function of KRAB zinc finger gene clusters in retrotransposon suppressionSemantic proximity Read ↗

Variable DNA methylation of transposable elements: the case study of mouse Early Transposons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.