Article
A novel locus for restless legs syndrome maps to chromosome 19p in an Irish pedigree.
Neurogenetics - 1 May 2012
Skehan Evelyn B, Abdulrahim Manal M A, Parfrey Nollaig A, Hand Collette K
Abstract excerpt
Restless legs syndrome (RLS) is a common, sleep-related movement disorder. The symptoms follow a circadian pattern, worsening in the evening or night, leading to sleep disruption and daytime somnolence. Familial forms of RLS have been described and usually display an autosomal dominant pattern of inheritance. To date, linkage analysis has identified nine RLS loci, but no specific causative gene has been reported....
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