Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q.

American journal of human genetics - 1 Dec 2001

Desautels A, Turecki G, Montplaisir J, Sequeira A, Verner A, Rouleau G A

Abstract excerpt

Restless legs syndrome (RLS) is a neurological disorder characterized by leg paresthesia associated with an irresistible urge to move that often interferes with nocturnal sleep, leading to chronic sleep deprivation. To map genes that may play a role in the vulnerability to RLS, a genomewide scan was conducted in a large French-Canadian family. Significant linkage was established on chromosome 12q, for a series of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Canada
Share to Chromosomes, Human, Pair 12
Share to France

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Dominant

Share to Genes, Recessive

Share to Lod Score

Share to Penetrance

Share to Restless Legs Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 11704926
DOI: 10.1086/324649
PMCID: PMC1235538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q.PMID 11704926Read ↗

Autosomal dominant restless legs syndrome maps on chromosome 14q.Semantic proximity Read ↗

Genomewide linkage scan identifies a novel susceptibility locus for restless legs syndrome on chromosome 9p.Semantic proximity Read ↗

A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13.Semantic proximity Read ↗

A novel locus for restless legs syndrome maps to chromosome 19p in an Irish pedigree.Semantic proximity Read ↗

Evidence for linkage of restless legs syndrome to chromosome 9p: are there two distinct loci?Semantic proximity Read ↗

Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity.Semantic proximity Read ↗

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.Semantic proximity Read ↗

[Advances in genetics of restless legs syndrome].Semantic proximity Read ↗

Autosomal-dominant locus for Restless Legs Syndrome in French-Canadians on chromosome 16p12.1.Semantic proximity Read ↗

Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome.Semantic proximity Read ↗

A novel locus for restless legs syndrome on chromosome 13q.Semantic proximity Read ↗

Restless legs syndrome: an update on genetics and future perspectives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.