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Article

Telomerase deficiency does not alter bleomycin-induced fibrosis in mice.

Experimental lung research - 1 Apr 2012

Degryse Amber L, Xu Xiaochuan C, Newman J Luke, Mitchell Daphne B, Tanjore Harikrishna, Polosukhin Vasiliy V, Jones Brittany R, McMahon Frank B, Gleaves Linda A, Phillips John A, Cogan Joy D, Blackwell Timothy S, Lawson William E

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is characterized by interstitial lung infiltrates, dyspnea, and progressive respiratory failure. Reports linking telomerase mutations to familial interstitial pneumonia (FIP) suggest that telomerase activity and telomere length maintenance are important in disease pathogenesis. To investigate the role of telomerase in lung fibrotic remodeling, intratracheal bleomycin was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22394286
DOI: 10.3109/01902148.2012.658148
PMCID: PMC4046256

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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