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Article

Telomerase and idiopathic pulmonary fibrosis.

Mutation research - 1 Feb 2012

Armanios Mary

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is the most common manifestation of telomere-mediated disorders. Germline mutations in the essential telomerase genes, hTERT and hTR, are the causal genetic defect in up to one-sixth of pulmonary fibrosis families. The presence of telomerase mutations in this subset is significant for clinical decisions as affected individuals can develop extra-pulmonary complications related...

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Identifiers

PMID: 22079513
DOI: 10.1016/j.mrfmmm.2011.10.013
PMCID: PMC3292861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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