Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a degenerative disease of the lungs with an average survival post-diagnosis of 2-3 years. New therapeutic targets and treatments are necessary. Mutations in components of the telomere-maintenance enzyme telomerase or in proteins important for telomere protection are found in both familial and sporadic IPF cases. However, the lack of mouse models that faithfully recapitulate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital Anomalies and Fetal Surgery
• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to Telomeres, Telomerase, and Senescence