Article
Analysis of the IL28RA locus as genetic risk factor for multiple sclerosis.
Journal of neuroimmunology - 1 Apr 2012
Lopez de Lapuente A, Alloza I, Goertsches R, Zettl U K, Urcelay E, Arroyo R, Comabella M, Montalban X, Antigüedad A, Vandenbroeck K
Abstract excerpt
Recently, we reported an association between a SNP in IL28RA and MS. Here, we performed a fine-mapping of the IL28RA locus by genotyping 10 haplotype-tagging SNPs in a Basque-Spanish population. In addition, based on shared genetic risk loci between autoimmune diseases, a psoriasis-associated SNP located at this locus, rs4649203, was genotyped in four independent populations, comprising a total of 2582 cases and...
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