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Article

Analysis of IL4R haplotypes in predisposition to multiple sclerosis.

Genes and immunity - 1 Mar 2004

Mirel D B, Barcellos L F, Wang J, Hauser S L, Oksenberg J R, Erlich H A

Abstract excerpt

We have investigated the association of multiple sclerosis (MS) with polymorphisms in the IL4R gene in 332 single-case MS families. IL4R encodes a subunit of the interleukin-4 receptor, a molecule important for T-cell development and differentiation, and is a gene shown to be associated with immune-related diseases such as asthma and type I diabetes. By genotyping two promoter and eight coding IL4R SNPs and...

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PMID: 14712310
DOI: 10.1038/sj.gene.6364048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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