A single amino acid change in E3 of ts1 mutant inhibits the intracellular transport of SFV envelope protein complex.

doi:10.1016/0042-6822(90)90133-c

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Article

A single amino acid change in E3 of ts1 mutant inhibits the intracellular transport of SFV envelope protein complex.

Virology - 1 Dec 1990

Syväoja P, Peränen J, Suomalainen M, Keränen S, Kääriäinen L

Abstract excerpt

At 39 degrees the envelope protein complex (E1-p62) of Semliki Forest virus mutant ts1 is arrested in the rough endoplasmic reticulum (RER). When the infected cultures are shifted to 28 degrees, the complex is transported to the cell surface. During the transport p62 is cleaved into E2 under cond...

Topics

Base Sequence
Cell Compartmentation
Cloning, Molecular
DNA
Fluorescent Antibody Technique
Genetic Vectors
Molecular Sequence Data
Mutation
Oligonucleotides
Protein Processing, Post-Translational
Restriction Mapping
Semliki forest virus
Structure-Activity Relationship
Viral Envelope Proteins

Source

Open in PubMed

Identifiers

PMID: 2238466
DOI: 10.1016/0042-6822(90)90133-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2238466-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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