Article
Defective transport of Sindbis virus glycoproteins in End4 mutant Chinese hamster ovary cells.
Journal of virology - 1 Mar 1991
Presley J F, Draper R K, Brown D T
Abstract excerpt
Mutant V.24.1, a temperature-sensitive derivative of Chinese hamster ovary cells, defines the End4 complementation group of mutants selected for resistance to protein toxins and has defective lysosomes at the restrictive temperature (P. A. Colbaugh, M. Stookey, and R. K. Draper, J. Cell Biol. 108:2211-2219, 1989). We have investigated the biosynthesis of Sindbis virus envelope glycoproteins in V.24.1 cells. When...
Topics
- Animals
- Cell Line
- Cricetinae
- Cricetulus
- Female
- Fluorescent Antibody Technique
- Kinetics
- Mutation
- Ovary
- Protein Processing, Post-Translational
- Sindbis Virus
- Viral Envelope Proteins
