Article
Events in the endoplasmic reticulum abrogate the temperature sensitivity of Sindbis virus mutant ts23.
Journal of virology - 1 Feb 1996
Carleton M, Brown D T
Abstract excerpt
Temperature-sensitive mutations in proteins produced at or heated to a nonpermissive temperature render the proteins defective in some aspect of their maturation into functional entities. The characterization of temperature-sensitive mutations in model proteins, such as virus membrane proteins, h...
Topics
- Animals
- Brefeldin A
- Cell Line
- Cyclopentanes
- Endoplasmic Reticulum
- Golgi Apparatus
- Membrane Fusion
- Membrane Glycoproteins
- Monensin
- Mutation
- Sindbis Virus
- Temperature
- Viral Envelope Proteins
- Virus Assembly