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Article

Growth and stability of a cholesterol-independent Semliki Forest virus mutant in mosquitoes.

Virology - 30 Sept 1999

Ahn A, Schoepp R J, Sternberg D, Kielian M

Abstract excerpt

Semliki Forest virus (SFV) is an enveloped alphavirus that is transmitted in the wild by mosquito vectors. In tissue culture cells, SFV requires cholesterol in the cell membrane both for virus membrane fusion and for the efficient exit of progeny virus from the cell. A previously isolated SFV mutant, srf-3, is strikingly less cholesterol-dependent for virus fusion, exit, and growth due to a single amino acid...

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Source

Identifiers

PMID: 10502523
DOI: 10.1006/viro.1999.9932

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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