Article
Mutation of pescadillo disrupts oligodendrocyte formation in zebrafish.
PloS one - 1 Jan 2012
Simmons Timothy, Appel Bruce
Abstract excerpt
BACKGROUND: In vertebrates, the myelin sheath is essential for efficient propagation of action potentials along the axon shaft. Oligodendrocytes are the cells of the central nervous system that create myelin sheaths. During embryogenesis, ventral neural tube precursors give rise to oligodendrocyte progenitor cells, which divide and migrate throughout the central nervous system. This study aimed to investigate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.