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Article

Antagonistic regulation of PAF1C and p-TEFb is required for oligodendrocyte differentiation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 13 Jun 2012

Kim Suhyun, Kim Jun-Dae, Chung Ah-Young, Kim Hyung-Seok, Kim Young-Seop, Kim Myoung-Jin, Koun Soonil, Lee You Mie, Rhee Myungchull, Park Hae-Chul, Huh Tae-Lin

Abstract excerpt

Oligodendrocytes are myelinating glial cells in the CNS and are essential for proper neuronal function. During development, oligodendrocyte progenitor cells (OPCs) are specified from the motor neuron precursor domain of the ventral spinal cord and differentiate into myelinating oligodendrocytes after migration to the white matter of the neural tube. Cell cycle control of OPCs influences the balance between...

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Identifiers

PMID: 22699901
DOI: 10.1523/JNEUROSCI.5344-11.2012
PMCID: PMC6703655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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