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Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal Activity

2024-12-27

Abstract excerpt

<h4>ABSTRACT</h4> To myelinate axons, oligodendrocyte precursor cells (OPCs) must stop dividing and differentiate into premyelinating oligodendrocytes (preOLs). PreOLs are thought to survey and begin ensheathing nearby axons, and their maturation is often stalled at human demyelinating lesions. Lack of genetic tools to visualize and manipulate preOLs has left this critical differentiation stage woefully understud...

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Literature Corpus work
e71f520f-e930-5726-94d2-d93d6f8950cf
DOI
10.1101/2024.12.27.630559
Open publication

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Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal ActivityDOI 10.1101/2024.12.27.630559
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