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Article

How to make an oligodendrocyte.

Development (Cambridge, England) - 1 Dec 2015

Goldman Steven A, Kuypers Nicholas J

Abstract excerpt

Oligodendrocytes produce myelin, an insulating sheath required for the saltatory conduction of electrical impulses along axons. Oligodendrocyte loss results in demyelination, which leads to impaired neurological function in a broad array of diseases ranging from pediatric leukodystrophies and cerebral palsy, to multiple sclerosis and white matter stroke. Accordingly, replacing lost oligodendrocytes, whether by...

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Identifiers

PMID: 26628089
DOI: 10.1242/dev.126409
PMCID: PMC4712837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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