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Article

Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae.

Genetics - 1 May 2012

Kremer Selena B, Kim Sunyoung, Jeon Jeong Ok, Moustafa Yara W, Chen Apeng, Zhao Jing, Gross David S

Abstract excerpt

Mediator is a modular multisubunit complex that functions as a critical coregulator of RNA polymerase II (Pol II) transcription. While it is well accepted that Mediator plays important roles in the assembly and function of the preinitiation complex (PIC), less is known of its potential roles in regulating downstream steps of the transcription cycle. Here we use a combination of genetic and molecular approaches to...

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Share to Gene Expression Regulation, Fungal
Share to HSP90 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22377631
DOI: 10.1534/genetics.111.135806
PMCID: PMC3338273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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