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Article

A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression.

Genetics - 1 Apr 2006

Singh Harpreet, Erkine Alexander M, Kremer Selena B, Duttweiler Harry M, Davis Donnie A, Iqbal Jabed, Gross Rachel R, Gross David S

Abstract excerpt

We report the results of a genetic screen designed to identify transcriptional coregulators of yeast heat-shock factor (HSF). This sequence-specific activator is required to stimulate both basal and induced transcription; however, the identity of factors that collaborate with HSF in governing noninduced heat-shock gene expression is unknown. In an effort to identify these factors, we isolated spontaneous...

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Identifiers

PMID: 16452140
DOI: 10.1534/genetics.105.052738
PMCID: PMC1456402

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