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Article

RAP1 protein activates and silences transcription of mating-type genes in yeast.

Genes & development - 1 Apr 1991

Kurtz S, Shore D

Abstract excerpt

RAP1 is a sequence-specific DNA-binding protein essential for cell growth. The occurrence of RAP1-binding sites in many promoter regions, the mating-type gene silencer elements, and telomeres suggests that RAP1 has multiple functions in the cell. To assess its role in transcription, temperature-sensitive mutations in RAP1 were generated. Analysis of rap1ts strains provides evidence that RAP1 functions in both...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 2010087
DOI: 10.1101/gad.5.4.616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RAP1 protein activates and silences transcription of mating-type genes in yeast.PMID 2010087Read ↗

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Molecular and genetic analysis of the toxic effect of RAP1 overexpression in yeast.Semantic proximity Read ↗

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length.Semantic proximity Read ↗

Rap1p is a negative regulator of the RAP1 gene.Semantic proximity Read ↗

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.Semantic proximity Read ↗

Structural and functional studies of the Rap1 C-terminus reveal novel separation-of-function mutants.Semantic proximity Read ↗

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.Semantic proximity Read ↗

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