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Article

Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations.

Antimicrobial agents and chemotherapy - 1 May 2012

Arendrup Maiken Cavling, Perlin David S, Jensen Rasmus Hare, Howard Susan Julie, Goodwin Joanne, Hope William

Abstract excerpt

We recently observed that the micafungin MICs for some Candida glabrata fks hot spot mutant isolates are less elevated than those for the other echinocandins, suggesting that the efficacy of micafungin may be differentially dependent on such mutations. Three clinical C. glabrata isolates with or without (S3) fks hot spot mutations R83 (Fks2p-S663F) and RR24 (Fks1p-S629P) and low, medium, and high echinocandin...

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Identifiers

PMID: 22354305
DOI: 10.1128/AAC.06369-11
PMCID: PMC3346593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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