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Article

Comparative effects of micafungin, caspofungin, and anidulafungin against a difficult-to-treat fungal opportunistic pathogen, Candida glabrata.

Antimicrobial agents and chemotherapy - 1 Mar 2012

Spreghini Elisabetta, Orlando Fiorenza, Sanguinetti Maurizio, Posteraro Brunella, Giannini Daniele, Manso Esther, Barchiesi Francesco

Abstract excerpt

The aim of this study was to compare the in vitro and in vivo activities of micafungin, caspofungin, and anidulafungin against Candida glabrata. The MICs against 28 clinical isolates showed that the overall susceptibilities to caspofungin and to micafungin were not statistically different in the absence of human serum, whereas the isolates were less susceptible to micafungin than to caspofungin in its presence....

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Identifiers

PMID: 22203604
DOI: 10.1128/AAC.05872-11
PMCID: PMC3294882

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