Article
FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance.
Antimicrobial agents and chemotherapy - 1 Dec 2010
Zimbeck Alicia J, Iqbal Naureen, Ahlquist Angela M, Farley Monica M, Harrison Lee H, Chiller Tom, Lockhart Shawn R
Abstract excerpt
Candida glabrata is the second leading cause of candidemia in the United States. Its high-level resistance to triazole antifungal drugs has led to the increased use of the echinocandin class of antifungal agents for primary therapy of these infections. We monitored C. glabrata bloodstream isolates from a population-based surveillance study for elevated echinocandin MIC values (MICs of ≥0.25 μg/ml). From the 490...
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