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Article

Preliminary evidence for an association between LRP-1 genotype and body mass index in humans.

PloS one - 1 Jan 2012

Frazier-Wood Alexis C, Kabagambe Edmond K, Borecki Ingrid B, Tiwari Hemant K, Ordovas Jose M, Arnett Donna K

Abstract excerpt

BACKGROUND/AIMS: The LDL receptor-related protein-1 gene (LRP-1) has been associated with obesity in animal models, but no such association has yet been reported in humans. As data suggest this increase in fat mass may be mediated through a mechanism involving the clearance of plasma triglyceride-rich lipoproteins (TGRL), where the LRP interacts with apolipoprotein E (ApoE) on chylomicron remnants, we aimed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22347399
DOI: 10.1371/journal.pone.0030732
PMCID: PMC3275600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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