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Article

The association between LRP-1 variants and chylomicron uptake after a high fat meal.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Nov 2013

Frazier-Wood A C, Kabagambe E K, Wojczynski M K, Borecki I B, Tiwari H K, Smith C E, Ordovas J M, Arnett D K

Abstract excerpt

BACKGROUND AND AIMS: In vitro studies suggest that low density lipoprotein receptor-related protein 1 (LRP1) plays a role in the secondary uptake of chylomicrons. In addition, in vivo studies using LRP-1 knockout mice show these animals exhibit delayed chylomicron clearance. Whether this is true in humans is unknown. We aimed to determine whether genetic variants in LRP-1 are associated with postprandial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23484911
DOI: 10.1016/j.numecd.2012.12.007
PMCID: PMC3686991

Genes

LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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