Article
Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study.
BMJ open - 7 Nov 2019
Shen Luqi, Cordero José F, Wang Jia-Sheng, Shen Ye, Li Shengxu, Liang Lirong, Zou Zhiyong, Li Changwei
Abstract excerpt
OBJECTIVES: The objective of this study was to evaluate the association of genetically determined leptin with lipids. DESIGN: We conducted a Mendelian randomisation study to assess a potential causal relationship between serum leptin and lipid levels. We also evaluated whether alcohol drinking modified the associations of genetically determined leptin with blood lipids. SETTING AND PARTICIPANTS: 3860 participants...
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